Cancer, a notorious cancer, has been among the top ten causes of death in Taiwan for decades. Its prevalence shows no signs of slowing down, and its treatment effects are not ideal. Why is this? James Chen, a doctor of natural medicine, said in《Renewing Mitochondria and Curing Chronic Diseases》 provides opinions.
A cancer cell experiment that subverts concepts
First of all, we need to define what cancer cells are. The so-called 'cancer cells' are cells that are out of control. The growth and division of normal cells are strictly controlled, and they will undergo apoptosis at a certain time; but cancer cells will continue to proliferate and divide, and will not undergo apoptosis. Mainstream medicine believes that this is caused by mutations in the genetic DNA in the cell nucleus.
Now, please take a look at an experiment that is enough to subvert past concepts. There are two cells on a petri dish, one is a normal cell and the other is a cancer cell. If the nucleus of the cancer cell (containing mutated DNA) is injected into the normal Among cells, after dividing, will a normal cell become a cancer cell or a normal cell?
I think this question should not be difficult to deduce. If cancer cells are caused by DNA mutations in the nucleus, when they divide, they will of course divide into cancer cells.
However, the results of this experiment were shocking: cells containing mutated DNA actually divided into normal cells with controlled growth. In other words, the cancer cell was cured.
How could it be so miraculous? How to explain this? Mainstream medicine has always believed that cancer is a genetic disease, that is, genetic DNA mutations in the nucleus. However, this experiment tells us that if the cytoplasm is normal, even if the nucleus is abnormal , the cells it divides are normal and their growth is strictly controlled. On the contrary, if the cytoplasm is abnormal, regardless of whether the nucleus is normal or not, the cells it divides are abnormal and their growth is uncontrolled.
Dr. Thomas Seyfried, PhD has done this experiment repeatedly, proving that the factor that determines whether a cell will divide into cancer cells or normal cells is not the DNA in the nucleus, but the cytoplasm. The mitochondria. If the mitochondria are normal, the cell will be normal, and even if the nucleus has mutated DNA, it will be repaired
Cancer is not a genetic disease, but a metabolic disease
The upstream cause of cancer is abnormal mitochondrial function. To be more precise, it is a problem with oxidative phosphorylation.
After glucose enters the cell, normal cells will first metabolize it into pyruvate in the cytoplasm (producing two ATPs), and then send the pyruvate into the mitochondria for aerobic respiration to generate energy (if everything goes well, up to 34 ATP).
But cancer cells usually ferment glucose into lactic acid in the cytoplasm, and in the presence of oxygen. This metabolic method is called aerobic fermentation or aerobic glycolysis. Humans use yeast to make wine, or to ferment dough, using this mechanism.
Why do cancer cells use aerobic glycolysis as energy? The main reason is that aerobic glycolysis occurs very quickly.
Cancer cells proliferate very quickly and require a lot of energy. It stands to reason that aerobic respiration of mitochondria can produce 34 ATP, which is a relatively large amount, but the speed is too slow, and the mitochondria in cancer cells are in In an unbalanced state, glucose cannot produce much energy.
Once the mitochondria are damaged, the cells will be induced to undergo aerobic glycolysis, fermenting glucose into lactic acid outside the mitochondria, and the cells will gradually become cancer cells.
In fact, as early as 1927, Otto Warburg proposed that the metabolism of cancer cells is different from that of normal cells, especially the consumption of glucose is greater than that of normal cells. This phenomenon is called 「The Warburg effect」 is the phenomenon described in the previous paragraph that cancer cells prefer aerobic glycolysis. Therefore, mainstream medicine has always believed that cancer is a metabolic disease. Until the 1970s, with the rise of genetic engineering, mainstream medicine began to believe that cancer is a genetic disease.
Dr. Warburg is no ordinary person. He is a contemporary and equally top scientist as Einstein. He has conducted thorough research on the metabolism of cancer cells and won the Nobel Prize in 1931. 【Recommended reading: Scientific research anecdotes》He survived cancer! The scapegoat for the theory that acidic body causes cancer , The legendary life of a Nobel laureate】
Warburg believes that the energy source of normal cells is aerobic respiration of mitochondria, and the products are carbon dioxide and water; while the energy source of tumor cell growth is lactic acid formed by the fermentation of glucose in the cytoplasm.
Currently, mainstream medicine does not accept the metabolic theory of Warburg and Seyfried, but this school does put forward some objective facts that force us to think about the following points:
1. Some cancers do not have genetic mutations.
2. Some carcinogens do not cause nuclear gene mutations.
3. Normal cells become cancerous at any time, but some do not develop further into cancer.
4. Ancient people and primitive tribes rarely suffered from cancer.
5. Transplantation experiments of cell nucleus and cytoplasm confirmed that cytoplasm has a decisive influence.
6. No matter how many genetic abnormalities are present in the nucleus of cancer cells, normal mitochondria can inhibit the growth of unregulated cells.
7. There is no single genetic mutation that is common to all cancers.
8. More than 90% of cancers have metabolic abnormalities.
Finally, more and more experiments have found that metabolites in blood, saliva, urine, and exhaled breath, such as acetate, lactate, serine, sarcosine ( Sarcosine, asparagine or choline can be used to detect cancer, but no genetic test can confirm cancer.
In addition, over the years, the technology of training puppies to diagnose cancer has become more and more mature. Dogs can be used to smell the skin, smell, urine, blood, and other body fluids of cancer patients, and can smell skin cancer, rectal cancer, and lung cancer. , ovarian cancer, prostate cancer, breast cancer, etc., especially breast cancer, the accuracy rate is as high as 100%. In addition to being non-invasive and economical, this method also proves that cancer is indeed a metabolic disease, and the cancer cells excrete. The metabolite has its unique smell.
The mitochondria of cancer cells are damaged
If you use an electron microscope to observe cancer cells, you will find that the mitochondria in the cancer cells have been damaged. If you use biochemical testing to detect the function of mitochondria in cancer cells, you will also find that the functions are damaged.The ridges in the mitochondria responsible for respiration, which are curved and wavy, are all messy and missing. How can these damaged cancer cells provide efficient aerobic respiration, and how can they repair the DNA in the cell nucleus?【Recommended reading: Before cancer and chronic diseases occur, mitochondria decline first! Dr. James Chen recommends「The Best Mitochondrial Strengthening Exercise」】
Seyfried further explained thatvarious abnormalities in cancer cells are caused by mitochondria being affected by various carcinogens, radiation, pollution, inflammation, age, viruses, etc., resulting in impaired function , and generate a large amount of reactive oxygen free radicals, which further attack and damage the cell nucleus. The mutation of the nuclear genes of cancer cells is the result of mitochondrial damage, not the cause of cancer. This causal relationship needs to be clarified.
Reactive oxygen free radicals can damage proteins and lipids. After being released from mitochondria, they will enter the nucleus from the cytoplasm and damage the DNA inside. So the genes or oncogene mutations we see are The downstream problem, and the upstream problem is that there is a problem in the mitochondria. The aerobic respiration of the mitochondria is not smooth enough, which is probably caused by mitochondrial damage.
Seyfried also explained that the reason why cancer cells metastasize is because after being engulfed by macrophages, abnormal mitochondria are swallowed up and fused into macrophages. That macrophage It turns into cancer cells and spreads in the body. This explanation is also completely consistent with mitochondrial heteroplasmy, that is, the mitochondrial function in a cell determines whether the cell is normal or not.
All cancer cells are particularly able to uptake glucose. This feature is well known and recognized by mainstream medicine. Not only that, mainstream medicine has made better use of this mechanism and developed positron emission tomography (PET), which uses glucose as a Media to diagnose cancer.
(Reference source: Dr. James Chen's《Renew mitochondria and cure chronic diseases》, the article was reprinted from the cancer.commonhealth.com.tw website【Research found that the mitochondria of cancer cells are damaged ! How to effectively repair mitochondria? Experts have the answer】, the text and subtitles have been edited)
